Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| RTV-231 | RTV231W32 | U.S. | 1994 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | RTV | 32 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V82F | I64V |
| >RTV231W32| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QILVEICGHKAIGTVLVGPTPFNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Molla, A | Ordered accumulation of mutations in HIV protease confers resistance to ritonavir. | Nat Med, 1996 |
| Wu, TD | Mutation patterns and structural correlates in human immunodeficiency virus type 1 protease following different protease inhibitor treatments. | J Virol, 2003 |
| Rhee, SY | HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. | J Infect Dis, 2005 |