Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6468 | CA134365 | U.S. | 2009 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | 52 |
| 2 | 3TC+AZT+EFV | 24 |
| 3 | Unknown | 461 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N | T215L, K219Q | Y181C, G190A | V179F | E6K, S68G, T69N, K101Q, K122E, D123DN, I135T, E204EK, Q207QH, R211RK, H221Y, A272P, K277R, T286A, E297K |
| >CA134365| codons 1-302 PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKNGNKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLQKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIFI CQYMDDLYVASDLEIGQHRTKIEKLRHHLLKWGFLTPDQKYQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEVIPLTKEAE LE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| F53LM | L10I, T12I, I13V, K20I, M36I, L63PS, I64L, A71V |
| >CA134364| codons 1-99 PQITLWQRPIVIVKIGGQLIEALLDTGADDTVLEEINLPGRWKPKMIGGIGGMIKVRQYD QISLEICGHKVIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Melikian, GL | Standardized comparison of the relative impacts of HIV-1 reverse transcriptase (RT) mutations on nucleoside RT inhibitor susceptibility. | AAC, 2012 |