<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
TW3452a TW3452a Taiwan 2004 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I13V, K14R, G16E, K20R, E35D, M36I, R41K, L63V, H69K, L89M  
>TW3452a| codons 1-99
PQITLWQRPIVTVRIEGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QIVIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E6K, K11T, E28K, K32E, V35T, E36A, T39K, K43E, K122E, D123S, I142V, S162HY, K173S, D177E, V179I, I195L, I202V, E203D, Q207A, R211K, E224D, V245Q  
>TW3452a| codons 1-246
PISPIKTVPVTLKPGMDGPKVKQWPLTKEKIEALTAICKEMEEEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQYSMTKILEPFRSQNPEIII
YQYMDDLYVGSDLELGQHRTKVDELRAHLLKWGFTTPDKKHQKDPPFLWMGYELHPDKWT
VQPIQL

References
Author Title Citation
Chang, SY Trends of antiretroviral drug resistance in treatment-naive patients with human immunodeficiency virus type 1 infection in Taiwan. J Antimicrob Chemother, 2008