Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA4460 | CA13276 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDI | 57 |
| 2 | 3TC+DDC+IDV | 135 |
| 3 | 3TC+DDC+NFV | 9 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L | L10LV, Q18QH, K43KN, L63P, I72V, V77I, Q92R, I93L |
| >CA13276| codons 1-99 PQITLWQRPVVTIKIGGHLKEALLDTGADDTVLEEMNLPGRWNPKLIGGIGGFIKVRQYD QIPIEICGHKAVGTVLIGPTPVNIIGRNLLTRLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K20KR, D121H, K122E, K166KR, K173R, D177E, Q207E, K277R, T286TA, P294Q, T296TP | R284RM |
| >CA13114| codons 1-299 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRRQNPEIVI YQYVDDLYVGSDLEIGQHRTKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLMGAKALTEVIQLPEEA |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |