<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
TW11250 TW11250 Taiwan 2006 HIV1 CRF01_AE Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, E35D, M36I, R41K, Q58QR, L63S, H69K, K70R, L89I  
>TW11250| codons 1-99
PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRRYD
QISIEICGKRAIGTVLVGPTPVNIIGRNILTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
  T215TA Y188YC   E6D, K11T, V35T, T39E, S105A, D123N, I135L, R172K, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245E Y127Y*
>TW11250| codons 1-246
PISPIDTVPVTLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKAVTVLDVGDAYFSVPL
DKNFRK*TAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKIKNPEMVI
YQYMDDLCVGSDLEIGQHRAKIEELRAHLLSWGFATPDKKHQKEPPFLWMGYELHPDRWT
VQPIEL

References
Author Title Citation
Chang, SY Trends of antiretroviral drug resistance in treatment-naive patients with human immunodeficiency virus type 1 infection in Taiwan. J Antimicrob Chemother, 2008