Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A32 | ARC-A32 | U.S. | 2004 | HIV1 | CRF01_AE | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, G17E, L19LM, K20IM, E35D, M36I, R41K, L63P, H69K, K70R, L89M |
| >ARC-A32| codons 1-99 PQITLWQRPLVTVRIGEQMMEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6D, K11T, V35T, T39K, K43E, K122E, D123S, I135T, I142V, K173I, Q174K, V179I, I202IV, Q207A, L210LM, R211S, K238R, V245E, L283I, E291D, V292I, I293V, A304E, E312T, I326V, I329V |
| >ARC-A32| codons 1-334 PISPIDTVPVTLKPGMDGPKVKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPDIII YQYMDDLYVGSDLEIGQHRTKVEELRAHLMSWGFTTPDKKHQKEPPFLWMGYELHPDRWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLIRGTKALTDIVPLTEEAE LELEENREILKTPVHGVYYDPSKDLVAEVQKQGQ |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, V32I, I72V, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, V201I, L234I | S283G |
| >ARC-A32| codons 1-288 FLDGIDKAQEEHERYHSNWRAMASDFNLPPVIAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVIHTDNGSN FTSAAVKAACWWANVQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
References
| Author | Title | Citation |
| Brennan, CA | Identification of human immunodeficiency virus type 1 non-B subtypes and antiretroviral drug-resistant strains in United States blood donors. | Transfusion, 2009 |