<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
148838k 148838k Uganda 1998 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 AZT 1
2 None 8

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E6D, V35T, K43KR, S48A, V60I, K122E, D123N, I135T, K173S, Q174K, D177E, V179I, T200TA, Q207E, V245Q, T286A, E291D, V292VI, I293V, P294A, E312D Q182Q*
>148838k| codons 1-324
PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEREGKIAKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIII
Y*YMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVALTEEAE
LELAENREILKDPVHGVYYDPSKD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, I15V, G16E, K20R, E35D, M36I, R41K, R57K, H69K, L89M  
>148838k| codons 1-99
PQITLWQRPLVTVRVEGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Eshleman, SH Survival of Ugandan infants with subtype A and D HIV-1 infection (HIVNET 012). JAIDS, 2002