<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 RTV 30

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V82F L33F I13V, K14R, E35D, M36L, N37D, D60E  
>RTV114W30| codons 1-99
PQITLWQRPLVTVRIGGQLKEALLDTGADDTVFEDLDLPGRWKPKMIGGIGGFIKVRQYE
QILIEICGHKAIGTVLVGPTPFNIIGRNLLTQIGCTLNF

References
Author Title Citation
Molla, A Ordered accumulation of mutations in HIV protease confers resistance to ritonavir. Nat Med, 1996
Wu, TD Mutation patterns and structural correlates in human immunodeficiency virus type 1 protease following different protease inhibitor treatments. J Virol, 2003
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005