<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
140727y 140727y Uganda 1998 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 AZT 1
2 None 8

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V8VA, K11T, K20R, V21I, E28EK, V35M, T39S, W88WC, K122E, D123S, K173S, Q174K, D177E, V179I, T200A, I202V, Q207A, R211KN, V245Q, E248D, A272AP, K281R, L283LI, T286A, E291D, V292I, I293V, P294T, E312D  
>140727y| codons 1-324
PISPIETAPVTLKPGMDGPRIKQWPLTKEKIKALMEICSEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFCEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIII
YQYMDDLYVGSDLEIGQHRAKVEELRAHLLNWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLIRGAKALTDIVTLTEEAE
LELAENREILKDPVHGVYYDPSKD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10IV, I13V, K14R, G16E, E35D, M36I, R41K, K45R, R57K, L63CR, H69K, K70R, L89M  
>140727y| codons 1-99
PQITLWQRPVVTVRIEGQLKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVKQYD
QIRIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Eshleman, SH Survival of Ugandan infants with subtype A and D HIV-1 infection (HIVNET 012). JAIDS, 2002