<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
117886a 117886a Uganda 1998 HIV1 D Plasma None

Treatment History
Order Regimen Weeks
1 AZT 1
2 None 8

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K22KN, V35T, T39TI, E40D, K49KR, V60I, K122E, I135V, D177E, I178M, Q207E, V245K, D250E, A272P, K277R, T286A, I293V L34LF
>117886a| codons 1-324
PISPIETVPVKLKPGMDGPKVNQWPLTEEKIKAFTEICIDMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMVI
YQYMDDLYVGSDLEIGQHRTKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10LV, I13IV, K14KR, I15IV, G16E, E35ED, M36I, N37ND, P39PS, R41K, L63X, H69KQ, I72IV, L89LM  
>117886a| codons 1-99
PQITLWQRPVVTVRVEGQLKEALLDTGADDTVLEDIDLSGKWKPKMIGGIGGFIKVRQYD
QIXIEICGQKAVGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Eshleman, SH Survival of Ugandan infants with subtype A and D HIV-1 infection (HIVNET 012). JAIDS, 2002