Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5353 | CA13075 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 75 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67DN, K70R | K219Q | K20R, V90I, A98S, K122E, D123N, I135AV, D177E, T200A, R211K, S251H, T286A, I293V, E297Q | T253TA |
| >CA13075| codons 1-301 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEIQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSANNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELRQHLLKWGFTTPDQKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDHWAVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVVPLTQEAE L |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12A, I13V, I15IV, E35D, N37T, I62V, I64V |
| >CA13239| codons 11-99 VAVKVGGQLKEALLDTGADDTVLEDMTLPGRWKPKMIGGIGGFIKVRQYDQVLVEICGHK AIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a Northern California clinic-based population. | J Infect Dis, 2001 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |