<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
MKK227 MKK227 Gabon 2006 HIV1 D Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L19I, R41K, K45KR, L63P, I64L, H69HQ, V77I  
>MKK227| codons 1-99
PQITLWQRPLVTIKIGGQIKEALLDTGADDTVLEEMNLPGKWKPRMIGGIGGFIKVRQYD
QIPLEICGQKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K20R, V35T, D121Y, I142N, K173E, Q174R, D177E, T200I, Q207E, R211K, F214L, V245C S48F, V60Y
>MKK227| codons 1-248
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTEMEKEGKIFKIGPENPYNTPY
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
YKDFRKYTAFTIPSINNETPGNRYQYNVLPQGWKGSPAIFQSSMTKILEPFRERNPEIVI
YQYMDDLYVGSDLEIGQHRIKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPICLPE

References
Author Title Citation
Mintsa-Ndong, A High HIV Type 1 prevalence and wide genetic diversity with dominance of recombinant strains but low level of antiretroviral drug-resistance mutations in untreated patients in northeast Gabon, Central Africa. ARHR, 2009