Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 476731T | 476731T | Uganda | 2007 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP | 6 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y181C | V35T, E36D, T39K, V60I, D121Y, K122E, I135T, T165I, D177E, T200I, Q207E, R211K, V245K, D250E, A272P, K275R, K277R, Q278N, L282C, L283I, I293V, I329V | P247E |
| >476731T| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICKEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL YEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRKQNPEIVI CQYMDDLYVGSDLEIGQHRIKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLEEKESWTVNDIQKLVGKLNWASQIYPGIRVRNLCKCIRGTKALTEVVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEVQKQGQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, N37S, R41K, I64V, H69Y |
| >476731T| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEEMSLPGKWKPKMIGGIGGFIKVRQYD QILVEICGYKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Church, JD | Analysis of nevirapine (NVP) resistance in Ugandan infants who were HIV infected despite receiving single-dose (SD) NVP versus SD NVP plus daily NVP up to 6 weeks of age to prevent HIV vertical transmission. | J Infect Dis, 2008 |