Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 458569M | 458569M | Uganda | 2007 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP | 6 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103N | V35T, V60I, K122E, D123N, I135T, S162Y, K173S, Q174K, V179I, Q207E, R211K, V245E, D250E, S251H, T286A, E291D, V292I, I293V, P294V, A327V |
| >458569M| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRSKNPDIII YQYMDDLYVGSDLEIGQHRTKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKEHWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVVLTEEAE LELAENREILKEPVHGVYYDPSKDLIVEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, K14R, L19Q, K20R, E35D, M36I, N37D, R41K, I64V, H69Y |
| >458569M| codons 1-99 PQITLWQRPLVSIRIGGQQREALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVRQYD QILVEICGYKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Church, JD | Analysis of nevirapine (NVP) resistance in Ugandan infants who were HIV infected despite receiving single-dose (SD) NVP versus SD NVP plus daily NVP up to 6 weeks of age to prevent HIV vertical transmission. | J Infect Dis, 2008 |