Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 428544C | 428544C | Uganda | 2007 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP | 6 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L33F | I13V, I15L, L19I, P39Q, R41K, L63T, E65D, I72T, V77I |
| >428544C| codons 1-99 PQITLWQRPLVTVKLGGQIKEALLDTGADDTVFEEMNLQGKWKPKMIGGIGGFIKVRQYD QITIDICGHKATGTVLIGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V106A | V35T, E44D, K49R, V60I, K122E, I135T, T165I, E169D, D177E, I202V, Q207A, R211K, F214L, D250E, S251C, A272P, K277R, L282C, L283I, R284K, I293V |
| >428544C| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKDGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSATVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILDPFRKQNPEIVI YQYMDDLYVGSDLEIGQHRTKVEELRAHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKECWTVNDIQKLVGKLNWASQIYPGIKVRQLCKCIKGTKALTEVVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQ |
References
| Author | Title | Citation |
| Church, JD | Analysis of nevirapine (NVP) resistance in Ugandan infants who were HIV infected despite receiving single-dose (SD) NVP versus SD NVP plus daily NVP up to 6 weeks of age to prevent HIV vertical transmission. | J Infect Dis, 2008 |