<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
428544C 428544C Uganda 2007 HIV1 D Plasma None

Treatment History
Order Regimen Weeks
1 NVP 6

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  L33F I13V, I15L, L19I, P39Q, R41K, L63T, E65D, I72T, V77I  
>428544C| codons 1-99
PQITLWQRPLVTVKLGGQIKEALLDTGADDTVFEEMNLQGKWKPKMIGGIGGFIKVRQYD
QITIDICGHKATGTVLIGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    V106A   V35T, E44D, K49R, V60I, K122E, I135T, T165I, E169D, D177E, I202V, Q207A, R211K, F214L, D250E, S251C, A272P, K277R, L282C, L283I, R284K, I293V  
>428544C| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKDGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSATVLDVGDAYFSVPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILDPFRKQNPEIVI
YQYMDDLYVGSDLEIGQHRTKVEELRAHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKECWTVNDIQKLVGKLNWASQIYPGIKVRQLCKCIKGTKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQ

References
Author Title Citation
Church, JD Analysis of nevirapine (NVP) resistance in Ugandan infants who were HIV infected despite receiving single-dose (SD) NVP versus SD NVP plus daily NVP up to 6 weeks of age to prevent HIV vertical transmission. J Infect Dis, 2008