<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
417659J 417659J Uganda 2007 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 NVP 6

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I13V, G16E, L19I, M36I, R41K, Q61H, L63V, H69K, L89M E35DY
>417659J| codons 1-99
PQITLWQRPVVTVKIEGQIKEALLDTGADDTVLEYINLPGKWKPKMIGGIGGFIKVRQYD
HIVIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    Y181YC, G190GA   K11T, V35T, D123N, I135T, K173S, Q174K, D177E, V179I, Q207A, R211S, F214L, V245M, A272P, T286A, I293V, P294T, E312D, P321S, D324E  
>417659J| codons 1-334
PISPIETVPVTLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKNFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIII
CQYMDDLYVASDLEIGQHRTKIEELRAHLLSWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVVTLTEEAE
LELAENREILKDPVHGVYYDSSKELIAEIQKQGQ

References
Author Title Citation
Church, JD Analysis of nevirapine (NVP) resistance in Ugandan infants who were HIV infected despite receiving single-dose (SD) NVP versus SD NVP plus daily NVP up to 6 weeks of age to prevent HIV vertical transmission. J Infect Dis, 2008