Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 380521-H | 380521-H | Uganda | 2007 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP | 6 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V106VA, Y181YC | K11T, K20R, V21I, V35T, T39K, K43E, D123N, K173S, D177E, V179I, T200A, I202V, Q207A, V245HQ, E248D, D250DE, T286A, E291D, V292VI, I293V, P294T |
| >380521-H| codons 1-334 PISPIETVPVTLKPGMDGPRIKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSATVLDVGDAYFSVPL DKNFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSQNPEIII CQYMDDLYVGSDLEIGQHRAKVEELRAHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, E35D, M36I, R41K, R57K, L63AT, H69K, L89M |
| >380521-H| codons 1-99 PQITLWQRPLVTVRIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QITIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Church, JD | Analysis of nevirapine (NVP) resistance in Ugandan infants who were HIV infected despite receiving single-dose (SD) NVP versus SD NVP plus daily NVP up to 6 weeks of age to prevent HIV vertical transmission. | J Infect Dis, 2008 |