Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 377986-M | 377986-M | Uganda | 2007 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP | 6 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, G16E, K20R, E35D, M36I, P39S, R41K, K45R, R57K, L63Q, H69K, L89M |
| >377986-M| codons 1-99 PQITLWQRPLVTVKIEGQLREALLDTGADDTVLEDINLSGKWKPRMIGGIGGFIKVKQYD QIQIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103KN, Y188YC | V35T, V60I, K122E, D123S, I135T, P170S, K173A, Q174K, D177E, V179I, T200I, Q207E, V245K, D250E, T286A, E291D, I293V, P294A, E297K, A304E, E312D |
| >377986-M| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILESFRAKNPEIII YQYMDDLCVGSDLEIGQHRIKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDVVALTKEAE LELEENREILKDPVHGVYYDPSKDLIAEIQKQGQG |
References
| Author | Title | Citation |
| Church, JD | Analysis of nevirapine (NVP) resistance in Ugandan infants who were HIV infected despite receiving single-dose (SD) NVP versus SD NVP plus daily NVP up to 6 weeks of age to prevent HIV vertical transmission. | J Infect Dis, 2008 |