Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 335346R | 335346R | Uganda | 2007 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP | 6 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K11S, V35T, E36ED, T39TS, K49R, K122E, D123N, I135T, I142V, K173AT, Q174K, D177E, V179I, Q207A, R211S, V245Q, A272PS, K281R, K287R, P294T, E312D | E29D |
| >335346R| codons 1-334 PISPIETVPVSLKPGMDGPKVKQWPLTEDKIKALTDICSEMEKEGKISRIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIII YQYMDDLYVGSDLEIGQHRTKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCRLLRGTRALTEVITLTEEAE LELAENREILKDPVHGVYYDPSKDLIAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I13V, E35D, M36I, R41K, R57K, L63I, H69K, L89M |
| >335346R| codons 1-99 PQITLWQRPIVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QIIIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Church, JD | Analysis of nevirapine (NVP) resistance in Ugandan infants who were HIV infected despite receiving single-dose (SD) NVP versus SD NVP plus daily NVP up to 6 weeks of age to prevent HIV vertical transmission. | J Infect Dis, 2008 |