Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 8770 | 8770 | Malawi | 2007 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V, T215F | K219Q | Y188L | T39E, S48T, K122E, D123S, I135T, I167V, K173A, Q174K, D177E, V179I, G196T, T200A, I202V, Q207E, R211RK, V245R |
| >8770| codons 38-247 CEEMEKEGKITKIGPENPYNTPVFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKVLEPFRAKNPEIIIYQYVDDLLVGSDLEITQHRAKVEELREHLLKWGFFTP DQKHQKEPPFLWMGYELHPDKWTVQPIRLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, G17GD, L19I, K20R, M36I, N37ND, R41K, H69K, L89M, I93L |
| >8770| codons 4-99 TLWQRPLVSIKVGDQIREALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYDQIL IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |