Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 8345 | 8345 | Malawi | 2007 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, M184V | D67G, K219E | K103N, Y181C | T39E, S48T, V60I, S68G, K122E, I135IT, K173T, Q174K, D177E, V179VI, T200EQ, E203K, Q207E, R211K, D218E, L228H, V245K |
| >8345| codons 38-247 CEEMEKEGKITKIGPENPYNTPIFAIKKKGGTRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRTKNPEIIICQYVDDLYVGSDLEIGQHRQKIKELREHLLKWGFTTP EEKHQKEPPFHWMGYELHPDKWTVQPIKLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19T, K20R, M36I, R41K, L63LI, H69K, V77I, L89M, I93L |
| >8345| codons 4-99 TLWQRPLVTIKVGGQTREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQII IEICGKKAIGTVLIGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |