Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 8821 | 8821 | Malawi | 2006 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, G16E, L19E, M36I, Q61N, L63A, I64L, H69K, K70R, L89M, I93L |
| >8821| codons 4-99 TLWQRPLVTIKVEGQEKEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYDNIA LEICGKRAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, M184V, T215Y | K103N | T39E, A98S, V118VI, K122E, D123S, I135IT, E138Q, S162C, K173A, Q174K, N175NY, D177E, I178IM, G196M, T200A, Q207E, H208HY, R211RK, V245T |
| >8821| codons 38-247 CEEMEKEGKISKIGPENPYNTPVFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP SGLKKNKSVTVLDVGDAYFSIPLDESFRKYTAFTIPSTNNQTPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFRAKYPEMVIYQYVDDLYVGSDLEIMQHRAKIEELREYLLKWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPITLP |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: High-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |