Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 7725 | 7725 | Malawi | 2006 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, Q151M, M184V | Y181C | V179D | T39E, E53D, S68G, K103R, V118I, K122E, D123S, I135T, T139A, S162D, K173T, T200A, Q207A, R211K, F214L, K223KQ, V245Q |
| >7725| codons 38-247 CEEMEKEGKISKIGPDNPYNTPVFAIKRKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKRKSVTVLDVGDAYFSIPLDESFRKYTAFTIPSTNNEAPGIRYQYNVLPMGWKGSP AIFQDSMTKILEPFRTQNPDIDICQYVDDLYVGSDLEIGQHRAKIEELRAHLLKWGLTTP DKKHQQEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19V, N37S, R41K, D60E, Q61E, L63P, H69K, V77I, I93L |
| >7725| codons 4-99 TLWQRPLVSIKVGGQVKEALLDTGADDTVLEEMSLPGKWKPKMIGGIGGFIKVRQYEEIP IEICGKKAIGTVLIGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |