Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 9456 | 9456 | Malawi | 2007 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T69DN, Q151M, M184V | A62V, F116Y | K103N, Y181C | T39E, S48T, K102N, K122E, D123G, T165I, K173I, Q174K, Q197E, T200A, I202V, E204Q, Q207E, R211K, F214L, L228R, V245Q | Q182H |
| >9456| codons 38-247 CEEMEKEGKITKIGPENPYNTPVFVIKKKDSNKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKNNKSVTVLDVGDAYYSVPLDEGFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSP AIFQSSMIKILEPFRIKNPDIVICHYVDDLYVGSDLEIGEHRAKVEQLREHLLKWGLTTP DKKHQKEPPFRWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19T, E35D, M36I, R41K, D60E, L63S, H69K, L89M, I93L | W6W*L |
| >9456| codons 4-99 TLLQRPLVSIKVGGQTKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYEQIS IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |