<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
9456 9456 Malawi 2007 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
T69DN, Q151M, M184V A62V, F116Y K103N, Y181C   T39E, S48T, K102N, K122E, D123G, T165I, K173I, Q174K, Q197E, T200A, I202V, E204Q, Q207E, R211K, F214L, L228R, V245Q Q182H
>9456| codons 38-247
CEEMEKEGKITKIGPENPYNTPVFVIKKKDSNKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKNNKSVTVLDVGDAYYSVPLDEGFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSP
AIFQSSMIKILEPFRIKNPDIVICHYVDDLYVGSDLEIGEHRAKVEQLREHLLKWGLTTP
DKKHQKEPPFRWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19T, E35D, M36I, R41K, D60E, L63S, H69K, L89M, I93L W6W*L
>9456| codons 4-99
TLLQRPLVSIKVGGQTKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYEQIS
IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Hosseinipour, MC The public health approach to identify antiretroviral therapy failure: High-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. AIDS, 2009