Isolate Data
Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
9455 | 9455 | Malawi | 2007 | HIV1 | C | Plasma | None |
Treatment History
Order | Regimen | Weeks |
1 | 3TC+D4T+NVP | NA |
RT Sequence
NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
M184V, T215Y | K101E, G190A | T39DE, S48T, K122E, D123S, S162C, K173T, Q174K, N175NY, T200A, Q207E, R211K, V245T |
>9455| codons 38-247 CEEMEKEGKITKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLEKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFRTKYPDIVIYQYVDDLYVASDLEIGQHRAKIEELREHLLKWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPITLP |
Protease Sequence
PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
T12S, I15V, L19I, M36I, P39Q, R41K, D60E, I62V, L63P, H69K, I72V, L89M, I93L |
>9455| codons 4-99 TLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLQGKWKPKMIGGIGGFIKVRQYEQVP IEICGKKAVGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
Author | Title | Citation |
Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: High-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |