Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 9433 | 9433 | Malawi | 2007 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, Q151M, M184V | A62V, V75I, F77L, F116Y | Y181V | T39E, S48ST, E53D, S68G, T69TI, K101Q, V118I, D121HY, K122E, I135T, K173A, Q174K, D177E, T200A, I202V, Q207D, L210F, R211K, F214L, V245Q |
| >9433| codons 38-247 CEEMEKEGKITKIGPDNPYNTPVFVIKRKDGIKWRKLIDLRELNKRTQDFWEVQLGIPHP AGLQKKKSVTVLDVGDAYYSIPLYEDFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSP AIFQSSMTKILEPFRAKNPEIVIVQYVDDLYVGSDLEIGQHRAKVEELRDHLFKWGLTTP DKKHQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, L19I, N37C, R41K, L63T, H69K, T74S, V77I, L89M, I93L |
| >9433| codons 4-99 TLWQRPLVSIKIGGQIKEALLDTGADDTVLEEMCLPGKWKPKMIGGIGGFIKVRQYDQIT IEICGKKAIGSVLIGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |