Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 9424 | 9424 | Malawi | 2007 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, K20R, E35D, M36L, R41K, L63P, H69K, V77I, L89M, I93L |
| >9424| codons 4-99 TLWQRPLVSIKVGGQIREALLDTGADDTVLEDLNLPGKWKPKMIGGIGGFIKVRQYDQIP IEICGKKAIGTVLIGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, K70KR, Q151M, M184I | V75I, F77FL, F116Y | Y181C | T39E, S48T, V60I, S68G, K122E, D123S, I132L, I135T, K173A, Q174K, D177E, I178M, T200A, E204D, R211K, H221Y, V245Q |
| >9424| codons 38-247 CEEMEKEGKITKIGPENPYNTPIFAIKRKDGTRWRKLIDLRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYYSVPLDESFRKYTAFTLPSTNNETPGIRYQYNVLPMGWKGSP AIFQSSMTKILEPFRAKNPEMVICQYIDDLYVGSDLEIGQHRAKIEDLRQHLLKWGFTTP DKKYQKEPPFLWMGYELHPDKWTVQPIQLP |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |