Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 9422 | 9422 | Malawi | 2007 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V, T215F | K219Q | K101E | Y188W | T39E, K49R, E53D, I94L, K122E, D123G, S162Y, K173A, Q174K, D177E, I178M, T200A, Q207N, R211K, V245Q |
| >9422| codons 38-247 CEEMEKEGKISRIGPDNPYNTPVFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGLPHP AGLEKKKSVTVLDVGDAYFSVPLDEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQYSMTKILEPFRAKNPEMVIYQYVDDLWVGSDLEIGQHRAKIEELRNHLLKWGFFTP DQKHQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, Q18E, L19T, K20R, E35D, M36I, R41K, H69K, L89M, I93L |
| >9422| codons 4-99 TLWQRPLVTIKVGGETREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYDQIL IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |