<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
9381 9381 Malawi 2007 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65KR, M184V   Y188L A98AG T39E, S48T, T69TN, D121H, K122E, T139A, K173T, Q174K, D177E, T200A, Q207E, R211K, L228LR, V245KQ D237DH
>9381| codons 38-247
CEEMEKEGKITKIGPENPYNTPVFAIKRKDSNKWRKLVDFRELNKRTQDFWEVQLGIPHP
GGLKKKKSVTVLDVGDAYFSVPLHEDFRKYTAFTIPSINNEAPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRTKNPEIVIYQYVDDLLVGSDLEIGQHRAKIEELREHLLKWGFTTP
DKKHQKEPPFRWMGYELHPHKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  L10LF I15V, L19I, M36I, R41K, H69K, T74S, L89M, I93L  
>9381| codons 4-99
TLWQRPFVTIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIL
IEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Hosseinipour, MC The public health approach to identify antiretroviral therapy failure: High-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. AIDS, 2009