Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 9378 | 9378 | Malawi | 2006 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | A62V, V75I, K219KN | Y181C, G190A | T39E, K122E, D123G, K173A, D177E, E194D, T200K, I202IV, R211RK, H221HY, D237E, V245Q |
| >9378| codons 38-247 CEEMEKEGKISKIGPENPYNTPVFVIKKKDSTKWRKLIDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRAQNPEIVICQYVDDLYVASDLDIGQHRKKVEELRQHLLKWGFTTP DNKYQKEPPFLWMGYELHPEKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19LI, E35D, M36I, R41K, I62V, H69K, T74S, L89M |
| >9378| codons 4-99 TLWQRPLVTIKVGGQIKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYDQVL IEICGKKAIGSVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |