<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
9363 9363 Malawi 2006 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74I, M184V, L210W, T215Y V75S, K219N Y181I V108VI T39E, E44D, S48T, V118I, K122E, E138A, A158S, S162A, K166R, K173A, V179I, T200A, Q207A, R211K, D218E, V245Q  
>9363| codons 38-247
CEELEKDGKITKIGPENPYNTPVFAIKKKNSTKWRKISDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTILDVGDAYFSIPLDEDFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSP
SIFQASMTRILEPFRAQNPDIIIIQYVDDLYVGSDLEIGQHRAKIEELRAHLWKWGFYTP
ENKHQKEPPFLWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, M36I, N37D, R41K, L63P, H69K, I93L  
>9363| codons 4-99
TLWQRPLVTIKVGGQLKEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYDQIP
IEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Hosseinipour, MC The public health approach to identify antiretroviral therapy failure: High-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. AIDS, 2009