<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
9359 9359 Malawi 2006 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, T69~ V75M, K219R V106M, Y181C   T39E, S48T, E53D, K122E, D123G, K173A, D177E, T200A, Q207E, R211K, F214L, H221Y, V245Q P157A
>9359| codons 38-247
CEEMEKEGKITKIGPDNPYNTPVFAIKRKDS~KWRKLMDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSMTVLDVGDAYFSVPLDEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSA
AIFQSSMTKILEPFRAQNPEIVICQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTP
DRKYQKEPPFLWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, L19T, K20R, M36I, R41K, L63V, H69K, I72IV, T74S, V77I, L89M, I93L  
>9359| codons 4-99
TLWQRPLVTIKVGGQTREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIV
IEICGKKAVGSVLIGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Hosseinipour, MC The public health approach to identify antiretroviral therapy failure: High-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. AIDS, 2009