<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
9326 9326 Malawi 2006 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, Q151M, M184V A62AV, V75I Y181I   T39E, S48ST, S68G, K122E, I132L, K173T, Q174K, T200A, I202IV, Q207E, F214L, V245E  
>9326| codons 38-247
CEEMEKEGKITKIGPENPYNTPVFVIKRKDGTKWRKLIDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTLPSINNETPGIRYQYNVLPMGWKGSP
AIFQSSMTKILEPFRTKNPDIVIIQYVDDLYVGSDLEIGQHRAKVEELREHLLRWGLTTP
DKKHQKEPPFLWMGYELHPDKWTVQPIELP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, K14R, I15V, L19I, M36I, R41K, L63V, H69K, T74A, L89M, I93L L76L*
>9326| codons 4-99
TLWQRPIVTIRVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIV
IEICGKKAIGAV*VGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Hosseinipour, MC The public health approach to identify antiretroviral therapy failure: High-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. AIDS, 2009