<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
9307 9307 Malawi 2006 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70KR, V75VM, M184V D67DG, F77FL, K219H Y181C V108I T39E, S48T, T69TN, K82KR, K122E, D123G, T139I, K173A, D177E, T200A, Q207E, L228R, V245K  
>9307| codons 38-247
CEEMEKEGKITKIGPENPYNTPVFAIKKKGSNRWRKLMDLRELNRRTQDFWEVQLGIPHP
AGLKKKKSVTILDVGDAYFSVPLDEGFRKYTAFTIPSINNEIPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRAQNPEIVICQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTP
DHKHQKEPPFRWMGYELHPDKWTVQPIKLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, M36I, N37ND, R41K, L63P, H69K, I93L  
>9307| codons 4-99
TLWQRPLVSIKVGGQIKEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYDQIP
IEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Hosseinipour, MC The public health approach to identify antiretroviral therapy failure: High-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. AIDS, 2009