<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
9306 9306 Malawi 2006 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70E, Q151M, M184V A62V, V75T Y181C, G190A   T39E, E40K, S48T, K122E, I135M, A158S, T165I, K173A, D177E, G196T, T200A, Q207E, R211K, F214L, H221Y, V245Q Q182H
>9306| codons 38-247
CEKMEKEGKITKIGPENPYNTPVFVIKKKNSTEWRKLTDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSMNNETPGIRYQYNVLPMGWKGSP
SIFQSSMIKILEPFRAQNPEIVICHYVDDLYVASDLEITQHRAKIEELREHLLKWGLTTP
DKKYQKEPPFLWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    K14T, I15V, L19IT, M36I, R41K, L63P, H69K, I93L  
>9306| codons 4-99
TLWQRPLVTITVGGQTKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIP
IEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Hosseinipour, MC The public health approach to identify antiretroviral therapy failure: High-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. AIDS, 2009