Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 9306 | 9306 | Malawi | 2006 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70E, V75T, Q151M, M184V | A62V | Y181C, G190A | T39E, E40K, S48T, K122E, I135M, A158S, T165I, K173A, D177E, G196T, T200A, Q207E, R211K, F214L, H221Y, V245Q | Q182H |
| >9306| codons 38-247 CEKMEKEGKITKIGPENPYNTPVFVIKKKNSTEWRKLTDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSMNNETPGIRYQYNVLPMGWKGSP SIFQSSMIKILEPFRAQNPEIVICHYVDDLYVASDLEITQHRAKIEELREHLLKWGLTTP DKKYQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| K14T, I15V, L19IT, M36I, R41K, L63P, H69K, I93L |
| >9306| codons 4-99 TLWQRPLVTITVGGQTKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIP IEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |