Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 9300 | 9300 | Malawi | 2005 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, K14N, I15V, L19I, M36I, L63T, H69K, I93L |
| >9300| codons 4-99 TLWQRPIVTINVGGQIKEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYDQIT IEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, T215Y | Y181C, G190A | T39E, S48T, K49KR, K122E, D123S, A158S, K173T, V179VI, G196K, T200A, Q207E, R211K, K238R, V245Q |
| >9300| codons 38-247 CEEMEKEGKITRIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP SIFQSSMTKILEPFRTQNPDIIICQYVDDLYVASDLEIKQHRAKIEELREHLLKWGFYTP DKKHQKEPPFLWMGYELHPDRWTVQPIQLP |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |