<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
9300 9300 Malawi 2005 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, K14N, I15V, L19I, M36I, L63T, H69K, I93L  
>9300| codons 4-99
TLWQRPIVTINVGGQIKEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYDQIT
IEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V, T215Y   Y181C, G190A   T39E, S48T, K49KR, K122E, D123S, A158S, K173T, V179VI, G196K, T200A, Q207E, R211K, K238R, V245Q  
>9300| codons 38-247
CEEMEKEGKITRIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
SIFQSSMTKILEPFRTQNPDIIICQYVDDLYVASDLEIKQHRAKIEELREHLLKWGFYTP
DKKHQKEPPFLWMGYELHPDRWTVQPIQLP

References
Author Title Citation
Hosseinipour, MC The public health approach to identify antiretroviral therapy failure: High-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. AIDS, 2009