Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 9458 | 9458 | Malawi | 2007 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, R41K, D60E, L63S, H69K, I72V, L89M |
| >9458| codons 4-99 TLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYEQIS IEICGKKAVGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70E, V75M, M184V, T215Y | D67S, T69G | Y181C | V108I | T39E, S48T, V118I, K122E, I135T, K173A, Q174K, D177E, T200A, Q207E, R211K, H221Y, V241M, V245Q |
| >9458| codons 38-247 CEEMEKEGKITKIGPENPYNTPVFAIKKKSSGEWRKLMDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTILDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRAKNPEIVICQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFYTP DKKYQKEPPFLWMGYELHPDKWTMQPIQLP |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |