Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 9457 | 9457 | Malawi | 2007 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, M184V, L210W, T215Y | K101E, Y181C | A98G, V108I | T39E, E44ED, S48T, K49R, V118VI, K122E, D123S, I135R, K173A, D177E, V179VI, T200A, E203K, Q207D, H208Y, R211K, H221Y, V245Q |
| >9457| codons 38-247 CEEMEKDGKITRIGPENPYNTPVFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP GGLEKKKSVTILDVGDAYFSIPLDESFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRAQNPEIIICQYVDDLYVGSDLEIGQHRAKIKELRDYLWKWGFYTP DKKYQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19T, R41K, L63P, H69K, V77I, L89M, I93L |
| >9457| codons 4-99 TLWQRPLVTIKVGGQTKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYDQIP IEICGKKAIGTVLIGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |