<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
9443 9443 Malawi 2007 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  L33LF I13V, L19T, K20R, M36I, R41K, L63V, H69K, V82VI, L89M, I93L  
>9443| codons 4-99
TLWQRPLVTVKIGGQTREALLDTGADDTVFEEINLPGKWKPKMIGGIGGFIKVRQYDQIV
IEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, M184V, T215Y   K101E, G190A   T39K, K43E, S48T, V60I, D123E, K173AT, D177E, T200A, Q207G, R211K, K238KR  
>9443| codons 38-247
CKEMEEEGKITKIGPENPYNTPIFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLEKKKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRTQNPEIVIYQYVDDLYVASDLEIGQHRAKIEELRGHLLKWGFYTP
DKKHQKEPPFLWMGYELHPDRWTVQPIVLP

References
Author Title Citation
Hosseinipour, MC The public health approach to identify antiretroviral therapy failure: High-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. AIDS, 2009