Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 9443 | 9443 | Malawi | 2007 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L33LF | I13V, L19T, K20R, M36I, R41K, L63V, H69K, V82VI, L89M, I93L |
| >9443| codons 4-99 TLWQRPLVTVKIGGQTREALLDTGADDTVFEEINLPGKWKPKMIGGIGGFIKVRQYDQIV IEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, M184V, T215Y | K101E, G190A | T39K, K43E, S48T, V60I, D123E, K173AT, D177E, T200A, Q207G, R211K, K238KR |
| >9443| codons 38-247 CKEMEEEGKITKIGPENPYNTPIFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLEKKKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRTQNPEIVIYQYVDDLYVASDLEIGQHRAKIEELRGHLLKWGFYTP DKKHQKEPPFLWMGYELHPDRWTVQPIVLP |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |