Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 9434 | 9434 | Malawi | 2007 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, Q18E, L19T, K20R, M36L, N37S, H69K, V77I, L89M, I93L |
| >9434| codons 4-99 TLWQRPLVTIKVGGETREALLDTGADDTVLEELSLPGRWKPKMIGGIGGFIKVRQYDQIL IEICGKKAIGTVLIGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, M184V, T215Y | Y181C | V108I | T39E, S48T, K122E, D123S, I135T, K173A, Q174K, D177E, T200A, Q207E, H221Y, V245Q |
| >9434| codons 38-247 CEEMEKEGKITKIGPENPYNTPVFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTILDVGDAYFSVPLDESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRAKNPEIVICQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFYTP DKKYQKEPPFLWMGYELHPDKWTVQPIQLP |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |