Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 9414 | 9414 | Malawi | 2007 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, T215Y | Y181C, G190A | K101H | T39A, E44ED, S48T, V118VI, K122E, D123S, T139R, K173I, Q174K, D177G, G196E, T200A, Q207E, L210LS, R211RK, F214FL, D218DE, V245Q |
| >9414| codons 38-247 CAEMEKDGKITKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLHKKKSVTVLDVGDAYFSIPLDESFRKYTAFTIPSINNERPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRIKNPGIVICQYVDDLYVASDLEIEQHRAKIEELREHLSKWGLYTP EKKHQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19IM, K20R, M36MI, N37ND, R41K, L63P, H69K, V77I, L89M, I93L |
| >9414| codons 4-99 TLWQRPLVSIKVGGQMREALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYDQIP IEICGKKAIGTVLIGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |