Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 9405 | 9405 | Malawi | 2007 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I13V, I15V, L19I, K20R, M36I, Q61E, L63S, H69K, L89M, I93L |
| >9405| codons 4-99 TLWQRPLVSVKVGGQIREALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYDEIS IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, Q151M, M184I | Y181C | T39D, S68G, K82KR, V90VI, K101KR, K122DE, D123G, K126KQ, I132L, S162Y, K173T, Q174K, T200A, Q207E, R211K, F214L, K223KE, V245Q |
| >9405| codons 38-247 CDEMEKEGKISKIGPENPYNTPVFAIKRKDGTKWRKLVDFRELNRRTQDFWEIQLGIPHP AGLRKKKSVTVLDVGDAYFSVPLDEGFRQYTAFTLPSINNETPGIRYQYNVLPMGWKGSP AIFQYSMTKILEPFRTKNPDIVICQYIDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTP DKKHQEEPPFLWMGYELHPDKWTVQPIQLP |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |