<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
9402 9402 Malawi 2007 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, T12S, I15V, L19I, M36I, R41K, R57K, Q61E, I62V, L63V, E65D, H69K, T74A, L89M  
>9402| codons 4-99
TLWQRPIVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVKQYDEVV
IDICGKKAIGAVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, M184V, T215F K219W Y181I K101H T39E, V60I, T69X, K122E, D123G, I135T, T139I, K173A, V179I, G196K, T200A, Q207E, H208Y, R211K, D218E, L228H, V245Q  
>9402| codons 38-247
CEELEKEGKISKIGPENPYNTPIFAIKKKNSXRWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLHKKKSVTVLDVGDAYFSVPLDEGFRKYTAFTIPSTNNEIPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRAQNPDIIIIQYVDDLYVGSDLEIKQHRAKIEELREYLLKWGFFTP
EWKHQKEPPFHWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Hosseinipour, MC The public health approach to identify antiretroviral therapy failure: High-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. AIDS, 2009