Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 9401 | 9401 | Malawi | 2007 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, K65R | Y181C | V179D | T39E, E44D, K122E, S162C, K173T, D177E, I178L, T200A, Q207D, R211K, V245Q |
| >9401| codons 38-247 CEELEKDGKISKIGPENPYNTPVFAIKRKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFRTQNPELDICQYMDDLYVGSDLEIGQHRAKIEELRDHLLKWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19IV, M36I, R41K, L63P, H69K, I72IL, I93L |
| >9401| codons 4-99 TLWQRPLVTIKVGGQVKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIP IEICGKKALGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |