<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
9395 9395 Malawi 2006 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V A62V V106M, Y181C   T39E, S48T, K122E, D123G, K173T, T200A, E203EK, Q207E, R211K, V245Q  
>9395| codons 38-246
CEEMEKEGKITKIGPENPYNTPVFVIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSMTVLDVGDAYFSVPLDEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRTQNPDIVICQYVDDLYVGSDLEIGQHRAKIKELREHLLKWGFTTP
DKKHQKEPPFLWMGYELHPDKWTVQPIQL

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    Q7K, I15V, L19I, M36I, R41K, L63T, H69K, T74S, L89M, I93L  
>9395| codons 7-99
KRPLVTIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQITIEI
CGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Hosseinipour, MC The public health approach to identify antiretroviral therapy failure: High-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. AIDS, 2009