Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 8983 | 8983 | Malawi | 2006 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74I, M184V, L210W, T215Y | K103N | A98G, V108I | T39E, E44D, S48T, S68SG, V118I, K122E, D123S, I135L, E138EG, I142T, K173AE, Q174R, D177E, I178M, G196D, T200A, E203K, Q207E, R211K, H221Y, V245Q |
| >8983| codons 38-247 CEELEKDGKITKIGPENPYNTPVFAIKKKDGTKWRKIVDFRELNKRTQDFWEVQLGIPHP GGLKKNKSVTILDVGDAYFSIPLDESFRKYTAFTIPSLNNGTPGTRYQYNVLPQGWKGSP AIFQSSMTKILEPFRERNPEMVIYQYVDDLYVGSDLEIDQHRAKIKELREHLWKWGFYTP DKKYQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, L19I, M36I, R41K, D60E, Q61E, L63P, H69K, L89M, I93L |
| >8983| codons 4-99 TLWQRPLVSIKIGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYEEIP IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |