Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 8947 | 8947 | Malawi | 2006 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q151M, T215Y | A62V, V75I, F77L, F116Y, K219Q | K103N, Y181C | T39D, S48T, S68G, T69TN, V111I, V118I, K122E, D123N, I142V, M164L, T165I, K173A, T200A, I202IV, Q207E, R211K, F214FL, V245Q |
| >8947| codons 38-247 CDEMEKEGKITKIGPENPYNTPVFVIKKKDGNKWRKLIDLRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDIGDAYYSIPLDENFRKYTAFTIPSINNETPGVRYQYNVLPMGWKGSP AIFQSSLIKILEPFRAQNPDIVICQYMDDLYVGSDLEIGQHRAKVEELREHLLKWGLYTP DQKHQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | L10F, L33F, N88D | T12S, I15V, L19I, K20T, E35D, M36I, Q61E, L63T, H69K, T74S, L89M, I93L |
| >8947| codons 4-99 TLWQRPFVSIKVGGQITEALLDTGADNTVFEDINLPGRWKPKMIGGIGGFIKVRQYDEIT IEICGKKAIGSVLVGPTPVNIIGRDMLTQLGCTLNF |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |