Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 8934 | 8934 | Malawi | 2007 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q151M, M184V | F116Y | K101E, G190A | T39E, S48T, K122E, D123G, S162C, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q |
| >8934| codons 38-247 CEEMEKEGKITKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLEKKKSVTVLDVGDAYYSVPLDEGFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSP AIFQCSMTKILEPFRAKNPEIVIYQYVDDLYVASDLEIGQHRAKIEELREHLLKWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19T, K20R, M36I, R41K, L63P, H69K, V77I, I93L |
| >8934| codons 4-99 TLWQRPLVSIKVGGQTREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIP IEICGKKAIGTVLIGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |