Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 8895 | 8895 | Malawi | 2006 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, Q151M | A62V, V75I, F77L, F116Y | Y181C, G190A | T39E, S48ST, S68G, T69I, V90I, V118I, K122E, D123N, R172K, K173T, D177DE, I178IL, T200A, E204K, Q207E, R211RK, F214L, K223Q, L228R, V245Q |
| >8895| codons 38-247 CEEMEKEGKITKIGPENPYNTPVFVIKRKDGIKWRKLIDLRELNKRTQDFWEIQLGIPHP AGLKKKKSVTVLDVGDAYYSIPLDENFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSP AIFQSSMTKILEPFKTQNPELVICQYMDDLYVASDLEIGQHRAKIEKLREHLLKWGLTTP DKKHQQEPPFRWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, E35D, M36I, R41K, H69K, T74S, L89M, I93IL |
| >8895| codons 4-99 TLWQRPLVSIKVGGQIKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYDQIL IEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |