Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 8732 | 8732 | Malawi | 2006 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65N, V75IT | A62V, K219R | K103N, Y181C | T39D, S68G, A98S, K122E, I132L, A158S, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q |
| >8732| codons 38-247 CDEMEKEGKISKIGPENPYNTPVFVIKNKDGTKWRKLTDFRELNKRTQDFWEVQLGIPHP SGLKKNKSVTVLDVGDAYFSVPLDEDFRKYTAFTLPSINNETPGIRYQYNVLPQGWKGSP SIFQSSMTKILEPFRAKNPEIVICQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTP DRKHQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, K14KR, I15V, L19I, M36I, N37D, R41K, L63S, H69K, I93L |
| >8732| codons 4-99 TLWQRPLVSIRVGGQIKEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYDQIS IEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |